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Analysis of institutional authors

Tortosa, MCorresponding Author

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January 5, 2026
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Article

Cyclopropylmethyl Boronic Esters as General Reagents in Transition-Metal Catalyzed Homoallylation Reactions

Publicated to: Journal Of The American Chemical Society. 147 (45): 41221-41228 - 2025-11-12 147(45), DOI: 10.1021/jacs.5c15781

Authors:

Lozano, B; Teresa, J; Fernandez, I; Tortosa, M
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Affiliations

Univ Autonoma Madrid, Inst Adv Res Chem Sci IAdChem - Author
Univ Autonoma Madrid, Organ Chem Dept - Author
Univ Complutense Madrid, Fac Chem, Organ Chem Dept - Author
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Abstract

Herein we disclose the use of cyclopropylmethyl boronates as general reagents in Negishi-type homoallylation reactions. This strategy provides a novel approach to generate enantioenriched homoallyl-Zn species through boron-to-zinc transmetalation. Subsequent sp2-sp3 cross-coupling offers a platform for the preparation of arenes, ketones, and 1,5-dienes containing a chiral homoallylic scaffold. The method has been applied to the late-stage functionalization of known drugs and the preparation of precursors of biologically relevant compounds. Mechanistic experiments and DFT calculations provide insight into the transmetalation/ring-opening sequence.
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Quality index

Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-03-11:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 3.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 3 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 20.
  • The number of mentions on the social network X (formerly Twitter): 34 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Leadership analysis of institutional authors

There is a significant leadership presence as some of the institution’s authors appear as the first or last signer, detailed as follows: First Author (Lozano, B) and Last Author (Tortosa Manzanares, Mariola).

the author responsible for correspondence tasks has been Tortosa Manzanares, Mariola.

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