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Analysis of institutional authors

Martin Rojas-Marcos, PatriciaAuthor

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November 7, 2025
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Article

Outcomes of transsphenoidal surgery for pituitary adenomas in Spain: a retrospective multicenter study

Publicated to: Frontiers In Endocrinology. 16 1529418- - 2025-02-21 16(), DOI: 10.3389/fendo.2025.1529418

Authors:

Paja, Miguel; Soto, Alfonso; Hanzu, Felicia A; Guerrero-Perez, Fernando; Camara, Rosa; Moure, Dolores; Galvez, Angeles; Simo-Servat, Andreu; Villar-Taibo, Rocio; Calatayud, Maria; Vicente, Almudena; Recio-Cordova, Jose M; Serra, Guillermo; Martin Rojas-Marcos, Patricia; Parra-Ramirez, Paola; Araujo-Castro, Marta; Librizzi, Soledad; Irigaray, Ana; Ollero, Dolores; Aznar, Silvia; Munoz, Fernando; Aulinas, Anna; Gonzalez-Fernandez, Laura; Garcia-Centeno, Rogelio; Egana, Nerea; Gonzalez-Vidal, Tomas; Menendez, Edelmiro; Delgado, Ana M; Abarca, Javier; Sottile, Johana; Pico, Antonio M; Novo, Cristina; Ortiz, Isabel; Tenorio, Carmen; de Leon, Ricardo; de Pablos-Velasco, Pedro; Crespo, Cristina; Penalver, David; Diaz-Soto, Gonzalo; Puig-Domingo, Manel; Biagetti, Betina; Neuroendocrinology Grp Spanish Endocrinol Nutr Soc
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Affiliations

- Author
Donostia Univ Hosp, Dept Neurol, Donostia San Sebastian, Spain - Author
Hosp Badalona Germans Trias & Pujol, Dept Endocrinol & Nutr, Badalona, Spain - Author
Hosp Clin Univ Valladolid, Dept Endocrinol & Nutr, Valladolid, Spain - Author
Hosp Dr Negrin Las Palmas De Gran Canaria, Dept Pathol, Las Palmas Gran Canaria, Spain - Author
Hosp Gen Univ Alicante, Dept Endocrinol, Alicante, Spain - Author
Hosp Gen Univ Alicante, Dept Neurosurg, Alicante, Spain - Author
Hosp Gregorio Maranon, Endocrinol & Nutr Dept, Madrid, Spain - Author
Hosp Santa Creu & Sant Pau, Endocrinol & Nutr Dept, Barcelona, Spain - Author
Hosp Univ 12 Octubre, Dept Endocrinol & Nutr, Madrid, Spain - Author
Hosp Univ Albacete, Endocrinol & Nutr Dept, Albacete, Spain - Author
Hosp Univ Basurto, Dept Endocrinol & Nutr, Bilbao, Spain - Author
Hosp Univ Bellvitge, Dept Endocrinol & Nutr, Barcelona, Spain - Author
Hosp Univ Burgos, Endocrinol & Nutr Dept, Burgos, Spain - Author
Hosp Univ Cent Asturias, Dept Endocrinol & Nutr, Oviedo, Asturias, Spain - Author
Hosp Univ Cruces, Endocrinol & Nutr Dept, Baracaldo, Bizkaia, Spain - Author
Hosp Univ Granada, Dept Endocrinol & Nutr, Granada, Spain - Author
Hosp Univ Granada, Dept Neurosurg, Granada, Spain - Author
Hosp Univ La Paz, Endocrinol & Nutr Dept, Madrid, Spain - Author
Hosp Univ Mutua Terrassa, Dept Endocrinol & Nutr, Terrassa, Spain - Author
Hosp Univ Navarra, Dept Endocrinol & Nutr, Dept Endocrinol & Nutr, Pamplona, Spain - Author
Hosp Univ Ramon & Cajal, Endocrinol & Nutr Dept, Madrid, Spain - Author
Hosp Univ Reina Sofia, Dept Endocrinol & Nutr, Cordoba, Spain - Author
Hosp Univ Salamanca, Endocrinol & Nutr Dept, Salamanca, Spain - Author
Hosp Univ Santiago De Compostela, Dept Hematol, Santiago De Compostela, Spain - Author
Hosp Univ Son Espases, Endocrinol & Nutr Dept, Mallorca, Spain - Author
Hosp Univ Toledo, Endocrinol & Nutr Dept, Toledo, Spain - Author
Hosp Univ Vall dHebron, Dept Endocrinol & Nutr, CIBERER U747 ISCIII, Barcelona, Spain - Author
Hosp Univ Virgen Rocio, Endocrinol & Nutr Dept, Seville, Spain - Author
IDIPAS, Hosp Clin, Endocrinol & Nutr Dept, Barcelona, Spain - Author
La Fe Univ Hosp, Dept Endocrinol & Nutr, Valencia, Spain - Author
St Pau Hosp, Neurosurg Dept, Barcelona, Spain - Author
Univ Basque Country UPV EHU, Med Dept, Bilbao, Spain - Author
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Abstract

Background The outcomes of transsphenoidal surgery (TSS) for pituitary adenoma (PA) depend on many factors, including the availability of an expert team and the volume of surgeries performed. Data on the outcomes of TSS for PA are scarce in our country. TESSPAIN evaluates TSS outcomes in Spanish centers to assess the influence of surgical volume and specialized neurosurgical teams on success and complication rates. Methods A retrospective, nationwide, study of Spanish centers performing TSS between January 2018 and December 2022. Centers were classified as high volume (HV) [n=11, defined as centers with recognized expertise in Spain or those performing more than 25 TSS/year] or non-HV. Data collection included surgical success rates, complications, and pituitary adenoma resectability (R-PA). Additional analyses evaluated the impact of dedicated neurosurgical teams (DNT) within HV centers. Results A total of 2815 TSS from 29 Spanish centers were included (1421 NSPA, 436 GH-secreting, 323 Cushing's disease, 127 PRL-secreting and 25 TSH-secreting PA). The overall success rate was 50.5%, 76.8% for R-PA. HV centers had a higher overall success rate (53.1 vs. 47.7%; p=0.03). Better TSS outcomes for NSPA accounted for this difference. The overall TSS complication rate was 22.1%, which was higher for NSPA than for SPA (25.0 vs. 17.7%). The overall complication rate of TSS for PA was significantly higher in non-HV centers than in HV centers (24 vs 20.4.0; p
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Keywords

ComplicationsExperiencePituitary adenomaSuccess rateSurgical complicationsSurgical experienceSurgical specializationTranssphenoidal surgery

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Frontiers in Endocrinology due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2025, it was in position 43/193, thus managing to position itself as a Q1 (Primer Cuartil), in the category Endocrinology & Metabolism.

Independientemente del impacto esperado determinado por el canal de difusión, es importante destacar el impacto real observado de la propia aportación.

Según las diferentes agencias de indexación, el número de citas acumuladas por esta publicación hasta la fecha 2026-04-05:

  • Google Scholar: 1
  • WoS: 1
  • Scopus: 1
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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-04-05:

  • The use, from an academic perspective evidenced by the Altmetric agency indicator referring to aggregations made by the personal bibliographic manager Mendeley, gives us a total of: 12.
  • The use of this contribution in bookmarks, code forks, additions to favorite lists for recurrent reading, as well as general views, indicates that someone is using the publication as a basis for their current work. This may be a notable indicator of future more formal and academic citations. This claim is supported by the result of the "Capture" indicator, which yields a total of: 12 (PlumX).

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

  • The Total Score from Altmetric: 10.
  • The number of mentions on the social network X (formerly Twitter): 15 (Altmetric).

It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

  • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
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Awards linked to the item

We are particularly grateful to all the patients included in the study and to the Spanish Society of Endocrinology for its support.
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